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Recombinant Human IL-17F protein (His tag)
SKU: PDEH100231-100
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Recombinant Human IL-17F protein (His tag)
| SKU # | PDEH100231 |
| Expression Host | E. coli |
Description
| Synonyms | Interleukin-17F;IL-17F;Cytokine ML-1;Interleukin-24;IL-24;IL17F;IL24 |
| Species | Human |
| Expression_host | E.coli |
| Sequence | Arg 31-Gln 163 |
| Accession | Q96PD4 |
| Mol_Mass | 14.5 kDa |
| AP_Mol_Mass | 16 kDa |
| Tag | C-His |
| Bio_Activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin level | Please contact us for more information. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis |
Background
Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. Today; IL-17 represents a family of structurally related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family; IL-17A through IL-17F; are secreted as homodimers. IL-17F also regulates cartilage matrix turnover and inhibits angiogenesis.