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Recombinant Human IL17RC Protein (aa 1-454, His Tag)(Active)
SKU: PKSH031012-100
Recombinant Human IL17RC Protein (aa 1-454, His Tag)(Active)
| SKU # | PKSH031012 |
| Expression Host | Baculovirus-Insect Cells |
Description
| Synonyms | UNQ, IL17RC, UNQ6118, PRO20040, PRO38901, IL17RL, IL17-RL, UNQ6118/PRO20040/PRO38901 |
| Species | Human |
| Expression Host | Baculovirus-Insect Cells |
| Sequence | Met 1-Ala 454 |
| Accession | NP_116121.2 |
| Calculated Molecular Weight | 49.6 kDa |
| Observed Molecular Weight | 60 kDa |
| Tag | C-His |
| Bio-activity | Measured by its ability to bind with recombinant human IL17A-His in a functional ELISA. Measured by its ability to bind with recombinant human 17A in a functional ELISA. |
Properties
| Purity | > 90 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from sterile 20mM Tris, 500mM NaCl, pH 7.4, 10% glycerol Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | Please refer to the printed manual for detailed information. |
Background
The hypomethylation within the IL17RC gene promoter in peripheral blood is not suitable for use as a clinical biomarker of AMD. This study highlights the need for considerable replication of epigenetic association studies prior to clinical application. methylation of IL17RC could play as a marker in choroidal neovascularization (CNV) and degeneration of retinal pigment epithelium (RPE) cells in vitro.