Recombinant Human LRG1 Protein (His Tag)
SKU: PKSH033295-50
Recombinant Human LRG1 Protein (His Tag)
SKU # | PKSH033295 |
Expression Host | HEK293 Cells |
Description
Synonyms | HMFT1766, LRG, LRG1, Leucine-rich alpha-2-glycoprotein |
Species | Human |
Expression Host | HEK293 Cells |
Sequence | Val36-Gln347 |
Accession | AAH34389.1 |
Calculated Molecular Weight | 35.4 kDa |
Observed Molecular Weight | 40-60 kDa |
Tag | C-His |
Bio-activity | Not validated for activity |
Properties
Purity | > 95 % as determined by reducing SDS-PAGE. |
Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
Formulation | Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 20mM NaCl, pH 7.5. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
Reconstitution | Please refer to the printed manual for detailed information. |
Background
Leucine-rich alpha-2-glycoprotein is a secreted protein and contains 8 LRR (leucine-rich) repeats and 1 LRRCT domain. The leucine-rich repeat (LRR) family of proteins; including LRG1; have been shown to be involved in protein-protein interaction; signal transduction; and cell adhesion and development. LRG1 is expressed during granulocyte differentiation. Levels of the LRG protein are markedly elevated in acute appendicitis and therefore could be used as a diagnostic aid.