Total Price: $0.00
Contact Information
Recombinant Human LRP12 Protein (His Tag)
SKU: PKSH032710-50
Recombinant Human LRP12 Protein (His Tag)
| SKU # | PKSH032710 |
| Expression Host | HEK293 Cells |
Description
| Synonyms | LRP-12, LRP12, Low-Density Lipoprotein Receptor-Related Protein 12, ST7, Suppressor of Tumorigenicity 7 Protein |
| Species | Human |
| Expression Host | HEK293 Cells |
| Sequence | Asn28-Ile488 |
| Accession | Q9Y561 |
| Calculated Molecular Weight | 52.5 kDa |
| Observed Molecular Weight | 68 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | Please refer to the printed manual for detailed information |
Background
Low-Density Lipoprotein Receptor-Related Protein 12 (LRP12) belongs to the LDLR family. LRP12 is a type I transmembrane protein annd widely expressed in heart, skeletal muscle, brain, lung, placenta and pancreas. LRP12 contains 2 CUB domain and 5 LDL-receptor class A domain. LRP12 has been shown to interact with GNB2L1, ZFYVE9 and ITGB1BP3. LRP12 is a receptor probably, which may be involved in the internalization of lipophilic molecules and/or signal transduction. In addition, LRP12 may act as a tumor suppressor.