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Recombinant Human LTBR/TNFRSF3 Protein (Fc Tag)
SKU: PKSH032718-50
Recombinant Human LTBR/TNFRSF3 Protein (Fc Tag)
| SKU # | PKSH032718 |
| Expression Host | HEK293 Cells |
Description
| Synonyms | D12S370, LTBR, Lymphotoxin-Beta Receptor, TNF-RIII, TNFCR, TNFR-III, TNFR3, TNFRSF3, Tumor Necrosis Factor C Receptor, Tumor Necrosis Factor Receptor 2-Related Protein, Tumor Necrosis Factor Receptor Superfamily Member 3, Tumor Necrosis Factor Receptor Type III |
| Species | Human |
| Expression Host | HEK293 Cells |
| Sequence | Gln31-Met227 |
| Accession | P36941 |
| Calculated Molecular Weight | 48.8 kDa |
| Observed Molecular Weight | 61 kDa |
| Tag | C-Fc |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | Please refer to the printed manual for detailed information. |
Background
Tumor necrosis factor receptor superfamily member 3; also known as Lymphotoxin-beta receptor;Tumor necrosis factor C receptor;Tumor necrosis factor receptor 2-related protein;Tumor necrosis factor receptor type III;LTBR;TNFCR; TNFR3 and TNFRSF3; is a member of the tumor necrosis factor (TNF) family of receptors. LTBR is a single-pass type I membrane protein and contains four TNFR-Cys repeats. It is expressed on the surface of most cell types; but not on T and B lymphocytes. LTBR and its ligand play a role in the development and organization of lymphoid tissue and transformed cells. Activation of LTBR can trigger apoptosis. In addition; LTBR can lead to the release of the cytokine interleukin 8.