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Recombinant Human MDH2 Protein (His Tag)
SKU: PKSH032731-50
Recombinant Human MDH2 Protein (His Tag)
| SKU # | PKSH032731 |
| Expression Host | HEK293 Cells |
Description
| Synonyms | MDH2, Malate dehydrogenase, mitochondrial |
| Species | Human |
| Expression Host | HEK293 Cells |
| Sequence | Ala25-Lys338 |
| Accession | P40926 |
| Calculated Molecular Weight | 34.0 kDa |
| Observed Molecular Weight | 33 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
| Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C. |
| Formulation | Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4. |
| Reconstitution | Not Applicable |
Background
Malate dehydrogenase, mitochondrial is a 338 amino acids protein that belongs to the LDH/MDH superfamily. MDH type 1 family. MDH2 catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. MDH2 is localized to the mitochondria and takes part in the malate-aspartate shuttle that functions in the metabolic coordination between cytosol and mitochondria. MDH2 is highly expressed in the adrenal system, small intestine, heart and pancreas.