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Recombinant Human MOB1A Protein (His Tag)
SKU: PKSH032759-50
Recombinant Human MOB1A Protein (His Tag)
| SKU # | PKSH032759 |
| Expression Host | E.coli |
Description
| Synonyms | C2orf6, MOB Kinase Activator 1A, MOB1A, MOB4B, MOBK1B, MOBKL1B, Mob1 Alpha, Mob1 Homolog 1B, Mob1A, Mps One Binder Kinase Activator-like 1B |
| Species | Human |
| Expression Host | E.coli |
| Sequence | Ser2-Arg216 |
| Accession | Q9H8S9 |
| Calculated Molecular Weight | 26.0 kDa |
| Observed Molecular Weight | 29 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | Please refer to the printed manual for detailed information. |
Background
MOB Kinase Activator 1A (MOB1A) belongs to the MOB1/phocein family, which acts as an activator of LATS1/2 in the Hippo signaling pathway, plays a key role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. MOBKL1B stimulates the kinase activity of STK38 and STK38L. MOBKL1B binds to and regulate downstream targets such as the NDR-family protein kinases and LATS1 kinase.