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Recombinant Human MORF4L2/MRGX Protein (His Tag)
SKU: PKSH032761-50
Recombinant Human MORF4L2/MRGX Protein (His Tag)
| SKU # | PKSH032761 |
| Expression Host | E.coli |
Description
| Synonyms | KIAA0026, MORF-Related Gene X Protein, MORF4L2, MRGX, Mortality Factor 4-Like Protein 2, Protein MSL3-2, Transcription Factor-Like Protein MRGX |
| Species | Human |
| Expression Host | E.coli |
| Sequence | Met 1-Leu288 |
| Accession | Q15014 |
| Calculated Molecular Weight | 33.4 kDa |
| Observed Molecular Weight | 36 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | Please refer to the printed manual for detailed information. |
Background
Mortality Factor 4-Like Protein 2 (MORF4L2) is a member of the mortality factor (MORF) family. MORF4L2 localizes in the nucleus, possessing a protein kinase C phosphorylation site and a tyrosine phosphorylation site. MORF4L2 interacts with the Rb tumor suppressor and it has histone deacetylase activity which can either repress or promote the activity of the B-Myb promoter depending on the tissue. In addition, MORF4L2 is involved in cell growth, regulation, and senescence.