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Recombinant Human PRRG2 protein (GST,His tag)
SKU: PDEH100317-100
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Recombinant Human PRRG2 protein (GST,His tag)
| SKU # | PDEH100317 |
| Expression Host | E. coli |
Description
| Synonyms | Transmembrane gamma-carboxyglutamic acid protein 2;PRRG2;Proline-rich gamma-carboxyglutamic acid protein 2;PRGP2;TMG2 |
| Species | Human |
| Expression_host | E.coli |
| Sequence | Arg 133-His 202 |
| Accession | O14669-1 |
| Mol_Mass | 32.6 kDa |
| AP_Mol_Mass | 35 kDa |
| Tag | N-GST-His |
| Bio_Activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin level | Please contact us for more information. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis |
Background
The protein encoded by this gene is a single-pass transmembrane protein containing an N-terminal gamma-carboxyglutamic acid (Gla) domain and tandem Pro/Leu-Pro-Xaa-Tyr (PY) motifs at its C-terminal end. The Gla domain is exposed on the cell surface while the PY motifs are cytoplasmic. The PY motifs of the encoded protein have been shown to interact with YAP1, a WW domain-containing protein. Therefore, it is thought that the encoded protein may be part of a signal transduction pathway. Two transcript variants encoding different isoforms have been found for this gene.