Recombinant Human RBP4 Protein
SKU: PKSH033427-50
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Recombinant Human RBP4 Protein
SKU # | PKSH033427 |
Expression Host | E.coli |
Description
Synonyms | PRBP, Plasma Retinol-Binding Protein, RBP, RBP4, RDCCAS, Retinol-Binding Protein 4 |
Species | Human |
Expression Host | E.coli |
Sequence | Glu19-Leu201 |
Accession | P02753 |
Calculated Molecular Weight | 21.2 kDa |
Observed Molecular Weight | 20 kDa |
Tag | None |
Bio-activity | Not validated for activity |
Properties
Purity | > 90 % as determined by reducing SDS-PAGE. |
Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
Formulation | Lyophilized from a 0.2 μm filtered solution of 50mM Tris-HCl, 10mM CaCl2, 150mM NaCl, pH 7.5. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
Reconstitution | Please refer to the printed manual for detailed information. |
Background
Retinol Binding Protein 4 (RBP4) is a member of the Lipocalin family and in the blood. RBP4 is the specific vector for retinol. RBP4 is expressed and secreted by adipose tissue; and is associated with insulin resistance. RBP4 delivers retinol from the liver stores to the peripheral tissues. In plasma; the RBP-retinol complex interacts with transthyretin to prevents its loss by filtration through the kidney glomeruli. Defects in RBP4 cause retinol-binding protein deficiency and can cause night vision problems.