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Recombinant Human RELT/TNFRSF19L Protein (Fc Tag)
SKU: PKSH033412-50
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Recombinant Human RELT/TNFRSF19L Protein (Fc Tag)
| SKU # | PKSH033412 |
| Expression Host | HEK293 Cells |
Description
| Synonyms | RELT, Receptor expressed in lymphoid tissues, TNFRSF19L, Tumor necrosis factor receptor superfamily member 19L |
| Species | Human |
| Expression Host | HEK293 Cells |
| Sequence | Ser26-Ala160 |
| Accession | Q969Z4 |
| Calculated Molecular Weight | 41.4 kDa |
| Observed Molecular Weight | 40-60 kDa |
| Tag | C-Fc |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
| Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C. |
| Formulation | Supplied as a 0.2 μm filtered solution of PBS, pH7.4. |
| Reconstitution | Not Applicable |
Background
Tumor necrosis factor receptor superfamily member 19L (TNFRSF19L), also known as Receptor expressed in lymphoid tissues and RELT, is a member of the TNF-receptor superfamily. TNFRSF19L is a single-pass type membrane protein and contains one TNFR-Cys repeat. TNFRSF19L is highly expressed in spleen, lymph node, thymus, peripheral blood leukocytes, bone marrow and fetal liver. It has been shown TNFRSF19L activates the NF-kappaB pathway and selectively binds TNF receptor-associated factor 1 (TRAF1). TNFRSF19L is capable of stimulating T-cell proliferation in the presence of CD3 signaling, which suggests its regulatory role in immune response.