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Recombinant Human SECTM1 Protein (His Tag)
SKU: PKSH033335-50
Recombinant Human SECTM1 Protein (His Tag)
| SKU # | PKSH033335 |
| Expression Host | HEK293 Cells |
Description
| Synonyms | K12, Protein K-12, SECTM1, Secreted and Transmembrane Protein 1 |
| Species | Human |
| Expression Host | HEK293 Cells |
| Sequence | Gln29-Gly145 |
| Accession | Q8WVN6 |
| Calculated Molecular Weight | 13.8 kDa |
| Observed Molecular Weight | 18-22 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | Please refer to the printed manual for detailed information. |
Background
Secreted and Transmembrane Protein 1 (SECTM1) is a transmembrane and secreted protein that belongs to the SECTM family. SECTM1 is expressed in a perinuclear Golgi-like pattern. It is detected at the highest levels in peripheral blood leukocytes and breast cancer cell lines. SECTM1 is considered to participate in thymocyte signaling and the hematopoietic/immune system processes. It is reported that SECTM1 is a broadly expressed; IFN-γ-inducible molecule; which functions as a potent costimulatory ligand for T cell activation and is synergistic with anti-CD28.