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Recombinant Human SOAT2/ACAT2 Protein (His&Trx Tag)
SKU: PKSH033082-50
Recombinant Human SOAT2/ACAT2 Protein (His&Trx Tag)
| SKU # | PKSH033082 |
| Expression Host | E.coli |
Description
| Synonyms | ACAT2, ACTL, Acetyl-CoA acetyltransferase cytosolic, Acetyl-CoA transferase-like protein, Cytosolic acetoacetyl-CoA thiolase |
| Species | Human |
| Expression Host | E.coli |
| Sequence | Met 1-Glu397 |
| Accession | Q9BWD1 |
| Calculated Molecular Weight | 59.1 kDa |
| Observed Molecular Weight | 60 kDa |
| Tag | N-Trx-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
| Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C. |
| Formulation | Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 100mM NaCl, 1mM DTT, 10% Glycerol, pH 8.0. |
| Reconstitution | Not Applicable |
Background
ACAT2 is a cytoplasmic enzyme which belongs to the thiolase family. ACAT2 takes part in lipid metabolism, lipoprotein assembly, catalyzing cholesterol esterification in mammalian cells. It is responsible for the synthesis of cholesteryl esters which are part of lipoproteins containing apoB. ACAT2 deficiency contributes to severe mental retardation and hypotonus.