Recombinant Human SQSTM1/ p62 protein (His tag)
SKU: PDEH100245-100
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Recombinant Human SQSTM1/ p62 protein (His tag)
SKU # | PDEH100245 |
Expression Host | E. coli |
Description
Synonyms | A170;DMRV;EBI 3 associated protein p60;EBIAP;FTDALS3;ORCA;OSF-6;OSIL;p60;P62b;PDB 3;PDB3;Sequestosome 1;SQSTM 1;STAP;STONE14;ZIP3 |
Species | Human |
Expression_host | E.coli |
Sequence | Ser 3-Lys 102 |
Accession | Q13501 |
Mol_Mass | 10.9 kDa |
AP_Mol_Mass | 15 kDa |
Tag | N-His |
Bio_Activity | Not validated for activity |
Properties
Purity | > 95 % as determined by reducing SDS-PAGE. |
Endotoxin level | Please contact us for more information. |
Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
Formulation | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
Reconstitution | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis |
Background
Adapter protein which binds ubiquitin and may regulate the activation of NFKB1 by TNF-alpha, nerve growth factor (NGF) and interleukin-1. May play a role in titin/TTN downstream signaling in muscle cells. May regulate signaling cascades through ubiquitination. Adapter that mediates the interaction between TRAF6 and CYLD (By similarity). May be involved in cell differentiation, apoptosis, immune response and regulation of K(+) channels.