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Recombinant Human STC2/Stanniocalcin 2 Protein (Fc Tag)
SKU: PKSH030584-100
Recombinant Human STC2/Stanniocalcin 2 Protein (Fc Tag)
| SKU # | PKSH030584 |
| Expression Host | HEK293 Cells |
Description
| Synonyms | STC-2, STCRP |
| Species | Human |
| Expression Host | HEK293 Cells |
| Sequence | Met 1-Arg302 |
| Accession | O76061 |
| Calculated Molecular Weight | 57.7 kDa |
| Observed Molecular Weight | 63 kDa |
| Tag | C-hFc |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 85 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from sterile PBS, pH 7.4 Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | Please refer to the printed manual for detailed information. |
Background
STC2 is a secreted; homodimeric glycoprotein which expressed in a wide variety of tissues. STC2 has an anti-hypocalcemic action on calcium and phosphate homeostasis. It may have autocrine or paracrine functions. Its C-terminus contains a cluster of histidine residues which may interact with metal ions. STC2 has 10 of its 15 cysteine residues conserved among stanniocalcin family members and is phosphorylated by casein kinase 2 exclusively on its serine residues. It may play a role in the regulation of renal and intestinal calcium and phosphate transport; cell metabolism; or cellular calcium/phosphate homeostasis.