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Recombinant Human THEM2/ACOT13 Protein (His Tag)
SKU: PKSH032042-50
Recombinant Human THEM2/ACOT13 Protein (His Tag)
| SKU # | PKSH032042 |
| Expression Host | HEK293 Cells |
Description
| Synonyms | ACOT13, Acyl-CoA Thioesterase 13, Acyl-Coenzyme A Thioesterase 13, THEM2, Thioesterase Superfamily Member 2 |
| Species | Human |
| Expression Host | HEK293 Cells |
| Sequence | Thr 2-Asn140 |
| Accession | Q9NPJ3 |
| Calculated Molecular Weight | 15.9 kDa |
| Observed Molecular Weight | 15 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 8% Sucrose, 100mM NaCl, 0.05% Tween 80, pH7.0. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | Please refer to the printed manual for detailed information. |
Background
Acyl-coenzyme A thioesterase 13, also known as Thioesterase superfamily member 2, ACOT13, THEM2 and PNAS-27, is a member of the thioesterase PaaI family. Acyl-CoA thioesterases catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. THEM2 is a cytoplasmic protein and exsis in a homotetramer. THEM2 has been identified as an interacting protein of phosphatidylcholine transfer protein. THEM2 also regulates hepatic lipid and glucose metabolism.