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Recombinant Human VSIG2 Protein (His Tag)
SKU: PKSH033363-50
Recombinant Human VSIG2 Protein (His Tag)
| SKU # | PKSH033363 |
| Expression Host | HEK293 Cells |
Description
| Synonyms | CT-Like Protein, CTH, CTXL, Cortical Thymocyte-Like Protein, V-Set and Immunoglobulin Domain-Containing Protein 2, VSIG2 |
| Species | Human |
| Expression Host | HEK293 Cells |
| Sequence | Val24-Ala243 |
| Accession | Q96IQ7 |
| Calculated Molecular Weight | 24.2 kDa |
| Observed Molecular Weight | 24-36 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | Please refer to the printed manual for detailed information. |
Background
V-Set and Immunoglobulin Domain-Containing Protein 2 (VSIG2) is presumably a 50-60 kDa single-pass type I transmembrane (glyco)protein which contains one Ig-like C2-type (immunoglobulin-like) domain and one Ig-like V-type (immunoglobulin-like) domain. VSIG2 is highly expressed in the stomach; colon; prostate; trachea and thyroid glands and weakly in bladder and lung. V-set domains are Ig-like domains resembling the antibody variable domain. V-set domains are found in diverse protein families; including immunoglobulin light and heavy chains; in several T-cell receptors such as CD2 (Cluster of Differentiation 2); CD4; CD80; and CD86; in myelin membrane adhesion molecules; in junction adhesion molecules (JAM); in tyrosine-protein kinase receptors; and in the programmed cell death protein 1 (PD1). It shows expression in stomach and prostate by Northern blot; and likely participates in cell adhesion. Human VSIG2 precursor is 327 amino acids in length.