Total Price: $0.00
Contact Information
Recombinant Mouse IL6 Protein(His tag)
SKU: PDMM100008-100
To better serve you, we would like to discuss your specific requirement.
Please Contact Us for a quote.
Recombinant Mouse IL6 Protein(His tag)
| SKU # | PDMM100008 |
| Expression Host | HEK293 Cells |
Description
| Synonyms | BSF, Interleukin, Interleukin HP, IFNB, B-cell hybridoma growth factor, BSF2, CDF, HGF, HSF, IFNB2, IL 6, Interleukin HP-1, Interleukin-6, Il-6, Il6 |
| Species | Mouse |
| Expression Host | HEK293 Cells |
| Sequence | Met1-Thr211 |
| Accession | P08505 |
| Calculated Molecular Weight | 23 kDa |
| Observed Molecular Weight | 25-30 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95% as determined by reducing SDS-PAGE. |
| Endotoxin | Please contact us for more information. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from sterile PBS, pH 7.4. Normally 5%-8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis. |
Background
Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism (Probable). Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway.The interaction with the membrane-bound IL6R and IL6ST stimulates 'classic signaling', whereas the binding of IL6 and soluble IL6R to IL6ST stimulates 'trans-signaling'. Alternatively, 'cluster signaling' occurs when membrane-bound IL6:IL6R complexes on transmitter cells activate IL6ST receptors on neighboring receiver cells.