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Recombinant Rat Complement C4b/C4b Protein (His tag)
SKU: PDMR100009-100
Recombinant Rat Complement C4b/C4b Protein (His tag)
| SKU # | PDMR100009 |
| Expression Host | HEK293 Cells |
Description
| Synonyms | C4, C4b, CO4, Complement C4, Complement C4 beta chain |
| Species | Rat |
| Expression Host | HEK293 Cells |
| Sequence | Lys20–Ser673 |
| Accession | P08649 |
| Calculated Molecular Weight | 71.8 kDa |
| Observed Molecular Weight | 70 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95% as determined by reducing SDS-PAGE. |
| Endotoxin | Please contact us for more information. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from sterile PBS, pH 7.4. Normally 5%-8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis. |
Background
Non-enzymatic component of C3 and C5 convertases and thus essential for the propagation of the classical complement pathway. Covalently binds to immunoglobulins and immune complexes and enhances the solubilization of immune aggregates and the clearance of IC through CR1 on erythrocytes.