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Recombinant Rat NT-proBNP Protein (GST tag)
SKU: PDER100029-100
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Recombinant Rat NT-proBNP Protein (GST tag)
| SKU # | PDER100029 |
| Expression Host | E. coli |
Description
| Synonyms | Natriuretic peptides B;ANFB_RAT;Nppb;Brain natriuretic factor prohormone;preproBNP;proBNP;Gamma-brain natriuretic peptide;Iso-ANP; |
| Species | Rat |
| Expression_host | E.coli |
| Sequence | His27-Arg76 |
| Accession | P13205 |
| Mol_Mass | 30.4 kDa |
| AP_Mol_Mass | 30 kDa |
| Tag | N-GST |
| Bio_Activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin level | Please contact us for more information. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis |
Background
Cardiac hormone that plays a key role in mediating cardio-renal homeostasis. May also function as a paracrine antifibrotic factor in the heart. Acts by specifically binding and stimulating NPR1 to produce cGMP, which in turn activates effector proteins that drive various biological responses. Likely involved in regulating the extracellular fluid volume and maintaining the fluid-electrolyte balance through natriuresis, diuresis, kaluresis and chloruresis.