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MSE PRO 2-Oxo-1,5-imidazolidinedicarboxylic acid, ≥97.0% Purity– MSE Supplies LLC

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MSE PRO 2-Oxo-1,5-imidazolidinedicarboxylic acid, ≥97.0% Purity - MSE Supplies LLC

MSE PRO 2-Oxo-1,5-imidazolidinedicarboxylic acid, ≥97.0% Purity

SKU: CM1369

  • £24300
  • Save £3400

MSE PRO™ 2-Oxo-1,5-imidazolidinedicarboxylic acid

, ≥97.0% Purity

MSE PRO™ 2-Oxo-1,5-imidazolidinedicarboxylic acid is a compound commonly used in organic synthesis and medicinal chemistry. It belongs to the class of imidazolidine-4-carboxylic acids, which are important intermediates in the synthesis of various pharmaceuticals and bioactive molecules. This compound is often utilized as a protecting group for the carboxylic acid functionality in peptide synthesis. The benzyloxycarbonyl (Cbz) group serves to temporarily shield the carboxyl group from unwanted reactions during peptide assembly, allowing for selective deprotection and manipulation of the peptide chain.

MSE Supplies offers various N-heterocyclic drug small molecules and other chemical reagents. Please contact us for bulk orders.

Technical Specifications:

CAS No. 59760-01-9
Chemical name (S)-3-((Benzyloxy)carbonyl)-2-oxoimidazolidine-4-carboxylic acid
Synonym(s)

  • (S)-(-)-2-Oxo-1,5-imidazolidinedicarboxylic acid 1-benzyl ester

  • (S)-3-((Benzyloxy)carbonyl)-2-oxoimidazolidine-4-carboxylic acid
Molecular formula C12H12N2O5                
Pack size

10 g (CM1369); 25 g (CM1370)
Molecular weight 264.23 g/mol
Density 
 		1.444±0.06 g/cm3 (Predicted)
Water (KF)
 		0.53%
OR[α] -63.3° (C=0.51 g/100ml MEOH)
pKa 3.22±0.20 (Predicted)
Purity ≥97.0% (NMR)
Appearance White to off-white solid
Storage  Store at room temperature

Note: KF refers to Karl Fisher, a method for measuring moisture content.

References:

[1] Hayashi, K., Nunami, K., Kato, J., Yoneda, N., Kubo, M., Ochiai, T., & Ishida, R. (1989). Studies on angiotensin converting enzyme inhibitors. 4. Synthesis and angiotensin converting enzyme inhibitory activities of 3-acyl-1-alkyl-2-oxoimidazolidine-4-carboxylic acid derivatives. Journal of medicinal chemistry, 32(2), 289-297.

[2] Bennion, C., Brown, R. C., Cook, A. R., Manners, C. N., Payling, D. W., & Robinson, D. H. (1991). Design, synthesis, and physicochemical properties of a novel, conformationally restricted 2, 3-dihydro-1, 3, 4-thiadiazole-containing angiotensin converting enzyme inhibitor which is preferentially eliminated by the biliary route in rats. Journal of medicinal chemistry, 34(1), 439-447.