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MSE PRO Glucose-6-Phosphate Dehydrogenase, High-Activity, Suspension– MSE Supplies LLC

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MSE PRO Glucose-6-Phosphate Dehydrogenase, High-Activity, Suspension

MSE PRO Glucose-6-Phosphate Dehydrogenase, High-Activity, Suspension

SKU: BO0205

  • £20400
  • Save £2300

MSE PRO™ Glucose-6-Phosphate Dehydrogenase, Lyophilized

The MSE PRO™ Glucose-6-phosphate dehydrogenase (G-6-PDH) consists of a His-Asp catalytic duplex and exists as a homodimer. Structurally, G-6-PDH contains a dinucleotide-binding region consisting of a Rossmann fold within the coenzyme-binding structural domain. It also has a larger beta + alpha structural domain with a unique aspartic acid residue at position 374. Glucose-6-phosphate dehydrogenase can use nicotinamide adenine dinucleotide phosphate (NADP+) or NAD+ as a coenzyme and has an important role in bacterial metabolism. Glucose-6-phosphate dehydrogenase catalyzes the conversion of glucose-6-phosphate to gluconolactone 6-phosphate as the first step in the pentose phosphate pathway.

Brand: MSE PRO™ 

Manufacturer: MSE Supplies LLC

MSE Supplies offers a variety of Biochemical Reagents. Please contact us for SDS, lead time and more information.

Applications:

It can be used in biochemical studies as an enzyme in erythrocyte glucose metabolism, which serves to maintain reduced glutathione and reduced coenzyme II (NADPH), maintains reducing capacity within erythrocytes, and prevents damage to erythrocytes such as hydrogen peroxide. In addition, it catalyzes the dehydrogenation reaction of glucose 6-phosphate, which can be used for enzymatic detection of NAD+ (or NADP+), glucose 6-phosphate, glucose phosphate isomerase, glucose phosphate translocase, and hexokinase. In combination with hexokinase, it can be used for the enzymatic detection of glucose.

Specifications:

SKU# BO0205
CAS No. 9001-40-5
EC No. 1.1.1.49
Storage buffer 3.7 M Ammonium Sulfate Solution
Biological Source Streptomyces enterica
Activity ≥600 NAD U/mg protein
Storage 2-8°C
Unit Definition One unit reduces 1 μmol of NAD per minute at 37°C, pH 7.8 with glucose-6-phosphate as substrate.
Note Product packaging is subject to change, the picture is for reference only