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Recombinant Human AIF1 Protein (His Tag)– MSE Supplies LLC

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Recombinant Human AIF1 Protein (His Tag)

SKU: PDEH100002-100

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Recombinant Human AIF1 Protein (His Tag)

 

SKU # PDEH100002
Expression Host E. coli

 

Description

Synonyms Allograft Inflammatory Factor 1;AIF-1;Ionized Calcium-Binding Adapter Molecule 1;Protein G1;AIF1;G1;IBA1
Species Human
Expression_host E.coli
Sequence Ser2-Pro147
Accession P55008
Mol_Mass 17.7 kDa
AP_Mol_Mass 16 kDa
Tag C-His

 

Properties

Purity > 90 % as determined by reducing SDS-PAGE.
Storage Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping This product is provided as lyophilized powder which is shipped with ice packs.
Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis

 

Background

Allograft Inflammatory Factor 1 (AIF1) contains two EF-hand domains and exists as a homodimer. AIF1 can be detected in T-lymphocytes and peripheral blood mononuclear cells. AIF1 functions as actin-binding protein that enhances membrane ruffling and RAC activation and can enhance the actin-bundling activity of LCP1. In addition, AIF1 plays a role in RAC signaling and in phagocytosis and may also in macrophage activation and function. AIF1 promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes and plays a role in vascular inflammation.