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Recombinant Human Annexin A6/ANXA6 Protein (His Tag)
SKU: PKSH032076-50
Recombinant Human Annexin A6/ANXA6 Protein (His Tag)
| SKU # | PKSH032076 |
| Expression Host | E.coli |
Description
| Synonyms | 67 kDa Calelectrin, ANX6, ANXA6, Annexin A6, Annexin VI, Annexin-6, CPB-II, Calphobindin-II, Chromobindin-20, Lipocortin VI, Protein III, p68, p70 |
| Species | Human |
| Expression Host | E.coli |
| Sequence | Ala2-Asp673 |
| Accession | P08133 |
| Calculated Molecular Weight | 76.9 kDa |
| Observed Molecular Weight | 60-90 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | Please refer to the printed manual for detailed information. |
Background
Annexin A6 (ANAX6) belongs to a family of calcium-dependent membrane and phospholipid binding proteins. Annexin A6 is a secreted protein and locates on the cell surface. Annexin A6 contains 8 annexin repeats separated by linking sequences of variable lengths. A pair of annexin repeats may form one binding site for calcium and phospholipid. ANXA6 is involved in the regulation of the release of Ca2+ from intracellular stores and may be associated with CD21. In addition, ANXA6 has been implicated in mediating the endosome aggregation and vesicle fusion in secreting epithelia during exocytosis.