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Recombinant Human FGFRL1 protein (His tag)
SKU: PDEH100403-100
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Recombinant Human FGFRL1 protein (His tag)
| SKU # | PDEH100403 |
| Expression Host | E. coli |
Description
| Synonyms | Fibroblast Growth Factor Receptor-Like 1;FGF Receptor-Like Protein 1;FGF Homologous Factor Receptor;FGFR-Like Protein;Fibroblast Growth Factor Receptor 5;FGFR-5;FGFRL1;FGFR5;FHFR |
| Species | Human |
| Expression_host | E.coli |
| Sequence | Met 31-Lys 360 |
| Accession | Q8N441 |
| Mol_Mass | 36.2 kDa |
| AP_Mol_Mass | 35 kDa |
| Tag | C-His |
| Bio_Activity | Not validated for activity |
Propertie
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin level | Please contact us for more information. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis |
Background
Fibroblast Growth Factor Receptor-Like 1 (FGFRL1) is a single-pass type I membrane protein that belongs to the FGF receptor family. The mature human FGFRL1 consists of a 354 amino acid extracellular domain (ECD) with 3 Ig-like C2-type domains, a 21 amino acid transmembrane segment, and a 134 amino acid cytoplasmic domain. FGFR1 expressed in various tissues, preferentially in cartilaginous tissues and pancreas. It highly expressed in the liver, kidney, heart, brain and skeletal muscle, weakly expressed in the lung, small intestine and spleen. FGFRL1 has a negative effect on cell proliferation.