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Recombinant Human ILT6/LILRA3 Protein (His tag)
SKU: PDMH100137-100
Recombinant Human ILT6/LILRA3 Protein (His tag)
| SKU # | PDMH100137 |
| Expression Host | HEK293 Cells |
Description
| Synonyms | CD85 antigen-like family member E, CD85e, HM31, HM43, ILT-6, ILT6, Immunoglobulin-like transcript 6, LIR-4, LIR-4 and Monocyte inhibitory receptor HM43/HM31, Leukocyte immunoglobulin-like receptor 4, Leukocyte immunoglobulin-like receptor subfamily A member 3 |
| Species | Human |
| Expression Host | HEK293 Cells |
| Sequence | Met1-Glu439 |
| Accession | Q8N6C8 |
| Calculated Molecular Weight | 48.2 kDa |
| Observed Molecular Weight | 65 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95% as determined by reducing SDS-PAGE. |
| Endotoxin | Please contact us for more information. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from sterile PBS, pH 7.4. Normally 5%-8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis. |
Background
Leukocyte immunoglobulin-like receptor subfamily A member 3 is also known as CD85 antigen-like family member E, Immunoglobulin-like transcript 6, ILT-6, Leukocyte immunoglobulin-like receptor 4, LIR-4 and Monocyte inhibitory receptor HM43/HM31. In humans, it is encoded by the LILRA3 gene. It acts as soluble receptor for class I MHC antigens. Binds both classical and non-classical HLA class I molecules but with reduced affinities compared to LILRB1 or LILRB2.It is detected in B-cells, natural killer (NK) cells, peripheral blood monocytes and lung.