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Recombinant Human NECAP2 Protein (His Tag)
SKU: PKSH032045-50
Recombinant Human NECAP2 Protein (His Tag)
| SKU # | PKSH032045 |
| Expression Host | E.coli |
Description
| Synonyms | Adaptin ear-binding coat-associated protein 2, NECAP endocytosis associated protein 2, NECAP2 |
| Species | Human |
| Expression Host | E.coli |
| Sequence | Met 1-Phe263 |
| Accession | Q9NVZ3 |
| Calculated Molecular Weight | 31.5 kDa |
| Observed Molecular Weight | 35 kDa |
| Tag | N-His & C-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
| Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C. |
| Formulation | Supplied as a 0.2 μm filtered solution of PBS, 2mM EDTA, 1mM DTT, pH 7.4. |
| Reconstitution | Not Applicable |
Background
NECAP2 belongs to the NECAP family. The WXXF motifs mediate binding of accessory proteins to the ear-domain of AP-1, GGAs and AP-2 through hydrophobic interactions. Adaptin ear-binding coat-associated protein 2 can interacts with AP1G1 and AP2A1 components of the adapter protein complex AP-1 and AP-2. It also interacts with the GAE domain proteins GGA1, GGA2 and GGA3.