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Recombinant Human Parvalbumin Alpha/PVALB Protein (His Tag)
SKU: PDEH100006-100
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Recombinant Human Parvalbumin Alpha/PVALB Protein (His Tag)
| SKU # | PDEH100006 |
| Expression Host | E. coli |
Description
| Synonyms | Parvalbumin Alpha;PVALB |
| Species | Human |
| Expression_host | E.coli |
| Sequence | Ser2-Ser110 |
| Accession | P20472 |
| Mol_Mass | 13.1 kDa |
| AP_Mol_Mass | 14 kDa |
| Tag | C-His |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis |
Background
Parvalbumin α (PVALB) is a member of the parvalbumin family. PVALB is a high affinity calcium ion-binding protein, with two EF hand domains. PVALB is structurally and functionally similar to calmodulin and troponin C, it can bind two calcium ions. Parvalbumin is thought to be involved in relaxation after contraction in muscle. Parvalbumin is expressed in a specific population of GABAergic interneurons, which are believed to have a role in maintaining the balance between excitation and inhibition in the cortex as well as the hippocampus.