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Recombinant Human POSTN Protein (His Tag)
SKU: PDEH100022-100
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Recombinant Human POSTN Protein (His Tag)
| SKU # | PDEH100022 |
| Expression Host | E. coli |
Description
| Synonyms | Fasciclin-I like;MGC119510;MGC119511;OSF 2;OSF-2;OSF2;Osteoblast specific factor 2 (fasciclin I like);Osteoblast specific factor 2;Osteoblast specific factor;Osteoblast-specific factor 2;PDLPOSTN;Periodontal ligament specific periostin;Periostin;Periostin isoform thy2;Periostin isoform thy4;Periostin isoform thy6;Periostin isoform thy8;Periostin osteoblast specific factor;PN;POSTN;POSTN;RP11 412K4.1 |
| Species | Human |
| Expression_host | E.coli |
| Sequence | Ala21-Leu365 |
| Accession | Q15063-1 |
| Mol_Mass | 38 kDa |
| AP_Mol_Mass | 40.3 kDa |
| Tag | N-His |
Properties
| Purity | > 85 % as determined by reducing SDS-PAGE. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from sterile 20mM Tris,1mM EDTA, pH 8.0 Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis |
Background
Periostin (POSTN,PN),originally named as osteoblast-specific factor 2 (OSF-2),is a 90-kDa secreted protein which is now classified as a matricellular protein. It is present in a wide variety of normal adult tissues and fetal tissues,and has a role in bone,tooth and heart development and function. Studies show that periostin is overexpressed in a broad range of human cancer types,includidng lung,ovary,breast and colon cancers. Recent evidence reveals that periostin is expressed by fibroblasts in the normal tissue and in the stroma of the primary tumour,and it is required to allow cancer stem cell maintenance.