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Recombinant Rhinopithecus roxellana IGF1/IGF‑I/IGF-1 protein (His tag)
SKU: PDEC100001-100
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Recombinant Rhinopithecus roxellana IGF1/IGF‑I/IGF-1 protein (His tag)
| SKU # | PDEC100001 |
| Expression Host | E. coli |
Description
| Synonyms | Insulin-like growth factor I;IGF1;Somatomedin |
| Species | Rhinopithecus roxellana |
| Expression_host | E.coli |
| Sequence | Gly 49-Met 153 |
| Accession | Q68LC0 |
| Mol_Mass | 11.4 kDa |
| AP_Mol_Mass | 13 kDa |
| Tag | N-His |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis |
Background
IGF-I induces the proliferation, migration, and differentiation of a wide variety of cell types during development and postnatally . IGF-I regulates glucose and fatty acid metabolism, steroid hormone activity, and cartilage and bone metabolism . It plays an important role in muscle regeneration and tumor progression . IGF-I/IGF-1 binds IGF-I R, IGF-II R, and the insulin receptor, although its effects are mediated primarily by IGF-I R . The IGF-I protein associates with IGF binding proteins thereby increasing its plasma half?life and modulating its interactions with receptors.